EUCTR2004-002295-41-GB进行中（未招募）1 期
A randomised phase II/III study of Docetaxel plus Prednisolone vs. Docetaxel plus Prednisolone plus Zoledronic acid vs. Docetaxel plus Prednisolone plus Strontium-89 vs. Docetaxel plus Prednisolone plus Zoledronic Acid plus Strontium-89 in Hormone Refractory Prostate Cancer metastatic to bone. - TRAPEZE: phase II/III efficacy and safety clinical trial in Hormone Refractory Prostate Cancer
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 757
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •1. Histologically / Cytologically proven prostate cancer or multiple sclerotic bone metastases with PSA>100ng/ml without histological confirmation.
- •2. Radiological evidence of bone metastasis
- •3. Documented disease progression
- •4. Life expectancy > 3 months
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1. Prior cytotoxic chemotherapy for HRPC, other than estramustine monotherapy
- •2. Known brain or Leptomeningal metastases
- •3. Symptomatic peripheral neuropathy > grade 2 (NCI CTC)
- •4. Any condition, which, in the opinion of the investigator, might interfere with the safety of the patient or evaluation of study objectives.
研究者
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