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Clinical Trials/NCT05038293
NCT05038293
Completed
Not Applicable

Efficacy of Plaque Removal of a Novel Brushing Device Compared to a Manual Toothbrush

University of Washington1 site in 1 country42 target enrollmentSeptember 17, 2021
ConditionsDental Plaque

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Dental Plaque
Sponsor
University of Washington
Enrollment
42
Locations
1
Primary Endpoint
Change From Baseline in Dental Plaque Removal Efficacy Using Turesky Modification of the Quigley-Hein Plaque Index
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The purpose of this research study is to compare how a novel, automated mouthpiece-based toothbrushing device removes dental plaque compared to a manual toothbrush.

Detailed Description

Plaque is one of the main etiological factors in dental decay and the principal etiological factor for periodontal diseases. Although toothbrushes have greatly evolved, dexterity is still the key component to an efficient cleaning routine. The primary goal is to examine 60 participants to determine the efficacy of a new powered teeth cleaning device designed to bypass the variability of individual dexterity compared with manual toothbrushing. This is a single-blind, randomized controlled trial. Sixty pediatric patients will be recruited for the study and randomized into treatment and control groups, subdivided into primary (20), mixed (20), and permanent dentition (20). Participants will be asked to abstain from brushing, flossing, gum or mouthwash use for 24 hours prior to the study visit. Plaque will be assessed using the Turesky Modification of the Quigley-Hein Plaque Index before and after a one-time brushing with the assigned study device. A soft tissue assessment will be conducted and intraoral photos taken pre- and post-brushing.

Registry
clinicaltrials.gov
Start Date
September 17, 2021
End Date
February 1, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Diane M Daubert RDH, MS, PhD

Clinical Associate Professor: School of Dentistry

University of Washington

Eligibility Criteria

Inclusion Criteria

  • Between the ages of 5-17
  • In good general health
  • Fluent in English
  • Parent or guardian willing and able to provide written informed consent
  • Have 16 scorable teeth (non-crown/bridge/or full amalgams)
  • Have had a dental cleaning and exam in the past 24 months

Exclusion Criteria

  • Advanced periodontal disease or severe gum disease
  • Mouth or teeth pain that prevents brushing in any areas
  • Intraoral piercings (tongue or lip) that cannot be removed
  • Non-controlled diabetes
  • Any autoimmune or infectious disease or any medical condition that would delay wound healing
  • Untreated visible cavities or untreated dental work
  • Oral or gum surgery in the previous 2 months
  • Take antibiotic premedication for dental procedures
  • Undergoing or require extensive dental or orthodontic treatment
  • Current smoker

Outcomes

Primary Outcomes

Change From Baseline in Dental Plaque Removal Efficacy Using Turesky Modification of the Quigley-Hein Plaque Index

Time Frame: baseline,1 minute after brushing

Average Change from baseline plaque index after brushing with the automated mouthpiece-based brushing device versus a manual toothbrush. The Turesky Modification of the Quigley-Hein Plaque Index evaluates 6 areas per tooth and gives a score from 0-5 with 0 being no plaque and 5 being the highest amount of plaque and the average score for all sites was used for analysis.

Secondary Outcomes

  • Change From Baseline in Presence of Soft Tissue Abrasion After Use of Automated Mouthpiece-based Brushing Versus Manual Toothbrush(baseline, 1 minute after brushing)

Study Sites (1)

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