Efficacy of Palatinose™ Versus Sucrose on Flow Mediated Dilation in Healthy Subjects With Mild Hypertension

Not Applicable

Completed

• Conditions: Overweight and Obesity
• Interventions: Dietary Supplement: isomaltulose; Dietary Supplement: sucrose

• Registration Number: NCT03986775
• Lead Sponsor: Beneo-Institute

Brief Summary

To determine the efficacy of Palatinose versus sucrose on Flow Mediated Dilation (FMD) in healthy subjects with mild hypertension.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-08-01
• Primary Completion: 2017-03-03
• Study Completion: 2017-08-09
• Status Verified: 2019-06
• Study First Submitted: 2019-06-11
• Study First Submitted QC: 2019-06-13
• Study First Posted: 2019-06-14
• Last Update Submitted: 2019-06-14
• Last Update Posted: 2019-06-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
citrus drink with isomaltulose	isomaltulose	-
citrus drink with sucrose	sucrose	-

Primary Outcome Measures

Name	Time	Method
Brachial ultrasound FMD scan	Baseline, 60 minutes, 120 minutes, 180 minutes	Changes in postprandial flow-mediated Dilation (endothelial function)

Secondary Outcome Measures

Name	Time	Method
Postprandial glycemic response	Baseline, 60 minutes, 120 minutes, 180 minutes	Postprandial glycemic response (Plasma samples)
Postprandial insulin response	Baseline, 60 minutes, 120 minutes, 180 minutes	Postprandial Insulin response (Plasma samples)