PACTR201302000483287已完成未知
EVALUATING PHARMACOKINETIC INTERACTIONS BETWEEN ARTEMISININ-BASED THERAPIES AND RIFAMPICIN-BASED TUBERCULOSIS TREATMENT IN AFRICAN PATIENTS
Infectious Diseases Institute, Makerer University College of Health Sciences0 个研究点目标入组 36 人开始时间: 2013年1月14日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 36
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Year(s) 至 65 Year(s)（—）
- 性别
- All
入选标准
- •¿Evidence of a personally signed and dated informed consent document indicating that the subject (or a legal representative) has been informed of all pertinent aspects of the study.
- •¿Subjects who are willing and able to comply with scheduled visits, treatment plan, laboratory tests, and other study procedures.
- •¿Aged between 18 to 65 years, inclusive.
- •¿Receiving TB-therapy containing rifampicin for at least 2 weeks
排除标准
- •¿Hypersensitivity to any of the study drugs or excipients
- •¿HIV infection
- •¿Malaria infection at screening
- •¿Serum hemoglobin < 8g/dL
- •¿Elevations in serum levels of alanine transaminase, aspartate transaminase or creatinine above 3 times the upper limit of normal
- •¿History of cardiac disease
- •¿Diarrhea lasting greater than one week
- •¿Use of herbal medications
- •¿Use of potent inhibitors of CYP3A4 including grapefruit juice within 1 week of first dose of study drug and for the duration of the study
- •¿Pregnant or lactating females
研究者
相似试验
已完成
不适用
Evaluation of Pharmacokinetic interaction between vitamin K1 and ezetimibeHealthy volunteerJPRN-UMIN000002327Department of Hospital Pharmacy, Hamamatsu University School of Medicine10
已完成
不适用
DRUG INTERACTION POTENTIAL BETWEEN trans-RESVERATROL AND SIMVASTATICTRI/2023/02/049518SRM COLLEGE OF PHARMACY , SRM INSTITUTE OF SCIENCE AND TECHNOLOGY20
已完成
不适用
Pharmacokinetic drug interaction study between rAltegraVIr and ATORvastatin (AVIATOR).AIDSHIV1004743810013317NL-OMON38561niversitair Medisch Centrum Sint Radboud24
已完成
1 期
Evaluation of pharmacokinetic interactions between the antidiabetic metformin andthe antibiotic trimethoprim.E11.90DRKS00000481niversität Heidelberg, Medizinische Fakultät24
尚未招募
4 期
Assesment of Pharmacokinetic drug Interaction and pharmacodynamic response of Clopidogrel Coadministered with IlaprazoleCTRI/2023/07/055363SRM College of Pharmacy SRM Institute of Science and Technology