Continuous high power short duration ablation for pulmonary vein isolation based on ablation index: Safety, efficacy and long-term durability

Phase 1

• Conditions: atrial fibrillation

• Registration Number: ChiCTR2400088816
• Lead Sponsor: The Second Affiliated Hospital of Xi'an Jiaotong University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1.Patients with symptomatic atrial fibrillation diagnosed by conventional 12-lead ECG or 24-hour Holter ECG, with poor symptom control or intolerance after treatment with at least one anti-arrhythmic drug, including paroxysmal atrial fibrillation and persistent atrial fibrillation<br>2. Patients with symptomatic atrial fibrillation prefer to radiofrequency ablation after fully weighing the benefits and risks before using antiarrhythmic drugs

Exclusion Criteria

1.age < 18 or >80 years old,<br>2.left atrium (LA) diameter > 50 mm,<br>3.the presence of a mechanical mitral valve prosthesis<br>4.impaired thyroid function<br>5.left ventricular ejection fraction < 40%<br>6.contraindication for anticoagulant therapy<br>7.current malignancy<br>8.prior catheter or surgical AF ablation<br>9.life expectancy < 1 year

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post-operative heart rhythm status;

Secondary Outcome Measures

Name	Time	Method
Procedure time;First-pass isolation rate of LPV and RPV;First-pass isolation time of LPV/RPV ;Bilateral pulmonary vein isolation time;