The Effect of Adjunct Vitamin a on Community-Acquired Pneumonia in Southern Iranian Children: a Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 105
- 试验地点
- 1
- 主要终点
- duration of hospitalization
研究概览
简要总结
This randomized clinical trial included 105 children with CAP who were admitted to Bandar Abbas Children's Hospital. Participants were randomly assigned to two groups: a control group receiving standard antibiotic therapy and an intervention group receiving standard antibiotics plus vitamin A (25,000 IU for 2 days). Key data collected included age, sex, duration of hospitalization, treatment duration, and daily Respiratory Index of Severity in Children (RISC) scores.
详细描述
Children to present with CAP symptoms
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 6 Months 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •children to present with CAP symptoms, including fever, cough, pulmonary rales, respiratory distress (age-adjusted tachypnea: >50 breaths per minute for infants under 1 year, >40 for ages 1-5 years, and >30 for those over 5 years), and radiographic findings indicative of pneumonia.
排除标准
- •underlying immunodeficiency, chronic respiratory conditions, concurrent use of immunosuppressive medications, prior high-dose vitamin A intake, and hospitalizations shorter than 24 hours
研究组 & 干预措施
a control group
the control group received standard antibiotic therapy
the intervention group received standard antibiotics plus adjunctive vitamin A supplementation
the intervention group received standard antibiotics plus adjunctive vitamin A supplementation (25,000 IU daily for two days)
干预措施: Vitamin A (Dietary Supplement)
结局指标
主要结局
duration of hospitalization
时间窗: Key data collected included age, sex, duration of hospitalization, treatment duration, and daily Respiratory Index of Severity in Children (RISC) scores.
Vitamin A supplementation was associated with a significant reduction in hospitalization duration in children with CAP, supporting its potential as an adjunct therapy.
Treatment duration daily Respiratory Index of Severity in Children (RISC) scores
时间窗: From enrollment to the end of treatment and discharge of patients ( 6 months)
daily Respiratory Index of Severity in Children (RISC) scores
次要结局
未报告次要终点
研究者
Mohammad Bagher Rahmati
Facualty memeber Oh HUMS
Hormozgan University of Medical Sciences