Effect of Anti-inflammatory (ITIS) Diet in Knee Osteoarthritis
- Conditions
- Osteoarthritis, Knee
- Interventions
- Dietary Supplement: ITIS diet
- Registration Number
- NCT05559463
- Lead Sponsor
- University of California, San Diego
- Brief Summary
To study the effect of anti-inflammatory diet on clinical and biological outcomes in patients with knee osteoarthritis
- Detailed Description
The investigators would like to evaluate how inflammation occurs in the joints of subjects with osteoarthritis, and identify molecules and bacteria that can predict whether a patients with knee osteoarthritis will have more or less pain . Blood, urine and stool will be evaluated in the laboratory and compared to their own samples after changes in diet. This is an exploratory study, which is meant to gather preliminary data about the quick effects of changes in diet and treatment on molecules in blood/urine and bacteria in stools. These studies can provide clues to the cause of disease and might ultimately lead to new therapies.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 30
- patients diagnosed of Knee Ostoeaarthritis
- without changes in treatment in the last 3 months
- food allergies
- pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description ITIS diet ITIS diet anti-inflammatory (ITIS) diet for 28 days
- Primary Outcome Measures
Name Time Method Change of baseline pain measured by visual analogue scale (0-10) after 28 days 28 days Change of baseline pain measured by visual analogue scale (0-10) after 28 days, being 0 no pain, and 10 the worse outcome
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UCSD
🇺🇸La Jolla, California, United States