Comparison of three methods of sputum clearance in patients with an acute exacerbation of chronic obstructive pulmonary disease (COPD).
- Conditions
- Acute exacerbation of chronic obstructive pulmonary disease (AECOPD)Respiratory - Chronic obstructive pulmonary disease
- Registration Number
- ACTRN12613000621718
- Lead Sponsor
- Brigitte Eastwood
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 75
Diagnosis of mild, moderate or severe COPD (as defined by spirometry) based on the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines
18 years or over.
Admitted to Middlemore Hospital medical wards.
Exacerbation with reported sputum based on GOLD definition from COPDx Guidelines (An exacerbation is an event in the natural course of the disease characterised by a change in the patient’s baseline dyspnoea, cough, and/or sputum that is beyond normal day-to-day variations, is acute in onset, and may warrant a change in regular medication in a patient with underlying COPD)
English speaking and reading
Consent to research
Non English speaking or reading
Unable to complete questionnaires or actively participate in treatment for any other reason (medical, physical, psychological)
Any previous PEP use at home
Receiving Bilevel positive airway pressure (BiPAP) treatment (as already receiving a form of positive pressure)
Any contraindications to PEP - large bullous disease, undrained pneumothorax
Any contraindications to airway clearance techniques, namely frank haemoptysis
Any patients previously recruited into this trial on any other admission
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method