Steroids Added to Dithranol and Narrow Band UVB(Ultraviolet B) (UVBnb) in Psoriasis
- Conditions
- Psoriasis
- Interventions
- Drug: Steroid active treatment
- Registration Number
- NCT01429870
- Lead Sponsor
- University of Zurich
- Brief Summary
Objective(s):
(i) To assess the effect of adjunctive topical steroids in the combined treatment with UVBnb and dithranol on the remission time after therapy till a relapse of psoriasis defined as 50% loss of PASI (Psoriasis Area and Severity Index) improvement obtained through the antecedent treatment.
(ii) To assess the impact of adjuvant topical steroids in the combined treatment with UVBnb and dithranol on the clearing time of psoriasis lesions under therapy (PASI 75).
* Trial with medicinal product
- Detailed Description
(i) To assess the effect of adjunctive topical steroids in the combined treatment with UVBnb and dithranol on the remission time after therapy till a relapse of psoriasis defined as 50% loss of PASI (Psoriasis Area and Severity Index) improvement obtained through the antecedent treatment.
(ii) To assess the impact of adjuvant topical steroids in the combined treatment with UVBnb and dithranol on the clearing time of psoriasis lesions under therapy (PASI 75).
* Trial with medicinal product
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Steroid active treatment Steroid active treatment Triamcinolone acetonide 0.1% in unguentum leniens topically Vehicle Steroid active treatment unguentum leniens topically
- Primary Outcome Measures
Name Time Method Relapse 50% PASI after treatment, time to PASI 75% on treatment 2 years Relapse 50% PASI after treatment, time to PASI 75% on treatment
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Dermatology Department
🇨🇭Zurich, Switzerland