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临床试验/ISRCTN36043780
ISRCTN36043780已完成未知

The effect of treatment of periodontitis on markers of cardiovascular diseases: a randomized, single blinded, clinical trial

Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrij University of Amsterdam (Netherlands)0 个研究点目标入组 200 人开始时间: 2013年9月25日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
200

研究概览

简要总结

  1. 2016 results in https://www.ncbi.nlm.nih.gov/pubmed/27169789 (added 29/01/2019) 2. 2017 results in https://www.ncbi.nlm.nih.gov/pubmed/28621003 (added 29/01/2019)

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Patients both males and females, being 20 years or older
  • 2. Patients affected by periodontitis defined as presence of 1/3 bone loss or more and presence of 6 mm pocket or more, with evidence of attachment loss at 2 or more teeth per quadrant and evidence of generalized bleeding

排除标准

  • 1. No systemic chronic diseases
  • 2. No acute medical interventions or diseases 4 weeks before baseline
  • 3. No pregnancy
  • 4. No chronic medications
  • 5. No antibiotics 6 months before intake and no repeated use of NSAID's medications 4 weeks before intake
  • 6. No hypersensitivity of contraindication for the use of amoxicillin and metronidazole

研究者

发起方
Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrij University of Amsterdam (Netherlands)

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