Interdisciplinary Evaluation of Acute Effects From Khalifa's Therapy at Patients With Fully Ruptured Anterior Cruciate Ligament (ACL).
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 10
- Locations
- 2
- Primary Endpoint
- Laser Doppler-Flow
Study Overview
Brief Summary
The primary hypothesis is that Khalifa's therapy has different acute effects in various organ systems i.e. proprioceptive, neuro-muscular, endogenous dopamine system, etc. These effects might indicate the pathway of the therapy.
Detailed Description
According to our previous study that evaluated the efficacy of Khalifa's therapy the investigators have seen that the therapy has acute effects which resulted in better knee function and later even in better healing of the ACL injury. This study should clear exactly which effects and pathways are involved in the therapy from multiple (interdisciplinary) point of views. Therefore the investigators will measure parameters that might be associated with this special technique directly before and after the therapy.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 49 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •totally ruptured ACL - MRI verified, 2 weeks old as a maximum
- •knee function: Any functional inhibition (stretching, bending or load)
- •BMI: 18-25
- •athletically active
Exclusion Criteria
- •any surgical procedures at the injured knee at any previous time
- •any acute surgical indication
- •diabetes mellitus and/or high blood pressure
- •any permanent drug treatment
Arms & Interventions
K-Pat
Getting one time one hour of Khalifa's therapy for ACL injury treatment.
Intervention: Khalifa Therapy (Other)
Outcomes
Primary Outcomes
Laser Doppler-Flow
Time Frame: 1 hour
Perfusion
IR Thermography
Time Frame: 1 hour
Infrared thermography, temperature
Knee function
Time Frame: 1 hour
IKDC Score KT-1000 test Clinical / physical examination
NIRS
Time Frame: 1 hour
Near infrared spectroscopy, Oxygen saturation
EEG
Time Frame: 1 hour
Electroencephalogram, brain waves
QST
Time Frame: 1 hour
Quantitative sensoric testing, pain
HRV
Time Frame: 1 hour
Heart rate variability, sympathicus/parasympathicus activation
Blood
Time Frame: 1 hour
Catecholamines endorphins standard blood parameters
SportsScience
Time Frame: 2 hours
Posturomed Motion capture proprioception muscle power range of motion
Secondary Outcomes
- Questionnaire(1 hour)
Investigators
Andreas Sandner-Kiesling , MD
Univ.Prof.Dr.
Medical University of Graz