A clinical trial to compare the antioxidant enzymes(superoxide dismutase,catalase and peroxidase)in patients of retinoblastoma localised to the eye and retinoblastoma with distance spread(metastasis)
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Patients with intraocular and metastatic retinoblastoma
- Registration Number
- CTRI/2011/08/001953
- Lead Sponsor
- Regional Institute of ophthalmology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
patients with retinoblastoma with age ranging from newborn to 8 year were included.
Exclusion Criteria
1. where written consent was not available from parents of the children
2.where the physical condition of the patient does not allow collection of blood sample by venepuncture.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Activity of three antioxidant enzymes[superoxide dismutase,catalase,peroxidase] were measured from blood samples obtained from cases of intraocular retinoblastoma and cases of metastatic retinoblastoma.Timepoint: Activity of three antioxidant enzymes were measured from blood samples obtained from cases of intraocular retinoblastoma and cases of metastatic retinoblastoma once a week for the study duration.
- Secondary Outcome Measures
Name Time Method noneTimepoint: not applicable