Clinical evaluation of dietary intake of tomato juice in preventing ultraviolet-induced (UV) erythema formation in Japanese subjects

Not Applicable

• Conditions: V-induced erythema

• Registration Number: JPRN-UMIN000018903
• Lead Sponsor: Kagome Co. Ltd.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-09-05
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Not provided

Exclusion Criteria

1) Subjects with apparent pigmentation, inflammation, and other diseases in the inside of both upper arms 2) Subjects with history of photo sensitivity 3) Subjects who habitually consume tomato juice or lycopene-rich foods 4) Subjects who use pharmaceuticals and quasi-drugs effective in the treatment of UV-induced skin pigmentation and chloasma 5) Female subjects who is breast-feeding or in pregnancy, or plan to get pregnant during this study period 6) Subjects with risk of allergy regarding to this study 7) Subjects with smoking habit 8) Subjects who habitually consume higher amount of alcohol (> avg 60 g alcohol/day) 9) Subjects who participated in other clinical trials within 2 months. 10) Subjects who are judged unsuitable for this study by principal investigator and doctors.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Erythema formation induced by UV radiation at 0, 8, and 12 weeks after beginning the study

Secondary Outcome Measures

Name	Time	Method
Increased level of malondialdehyde in stratum corneum, increased pigmentation, and changes in serum carotenoids (lycopene, beta-carotene, etc. and vitamin E)