Exploration of the modulation of skin microbiota and odor components by introduction of stress in healthy male subjects.

Completed

Conditions: Stress-induced malodor formation
Malodor
Sweat odor

Registration Number: NL-OMON44360

Lead Sponsor: Procter & Gamble

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 30

Inclusion Criteria

1. Male
2. Age 18-34 yrs
3. BMI between 18,5-25 kg/m2
4. Healthy as assessed by the NIZO lifestyle and health questionnaire (*Verklaring leefgewoonten en gezondheid*).
5. Non-smoking
7. Access to internet

Exclusion Criteria

1. Alcohol consumption > 15 units/week and > 3/day.
2. Drug abuse
3. Heavy exercise or sports training > 10 hours/week.
4. Hyperhidrosis , Hypohidrosis or Anhidrosis
5. Known allergy to cosmetics
6. Psychiatric disorders
7. Use of anti-anxiety medications or beta-blockers, statins or blood pressure medication
8. Use of antibiotics during the six (6) months prior to study start.
9. Use of topical medications in underarm area during two (2) weeks prior to study start
10. Active eczema or psoriasis on any portion of the body.;Procedural:
1. Personnel of the research institute(s) involved in execution of the study, their partner and their first and second degree relatives
2. Not having a general practitioner, not allowing disclosure of participation to the general practitioner or not allow to inform the general practitioner about abnormal results.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The aim of this study is to assess whether the adapted Sternberg short-term<br /><br>working memory task (STMST) is an effective method to induce malodor formation<br /><br>by emotional stress, as assessed by expert assessments of stress-induced<br /><br>malodor formation in the armpits of healthy male volunteers.</p><br>

Secondary Outcome Measures