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The TOTAM study

Recruiting
Conditions
Adjuvante behandeling van oestrogeenreceptor positieve (HR+) borstkanker.
Registration Number
NL-OMON23682
Lead Sponsor
Erasmus Medical Center, Rotterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Adult women (≥ 18 years of age) who are planned to start adjuvant tamoxifen therapy.

2. WHO Performance Status ≤ 1

Exclusion Criteria

1. Woman who are pregnant or breast feeding;

2. Endometrial cancer (diagnosis < 3 years ago)

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To prove that TDM of tamoxifen is feasible in clinical practice.
Secondary Outcome Measures
NameTimeMethod
-Toxicity<br>-Dose related adverse events<br>-Compliance<br>-Cost effectiveness<br>-Incidence of tamoxifen induced non-alcoholic fatty liver disease
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