Comparison of tramadol and dexmedetomidine in treatment of post neuraxial anaesthesia shivering
试验速览
- 阶段
- Unknown
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- control of shivering
研究概览
简要总结
Shivering after neuraxial blockade should be managed efficiently to reduce its complications. Thus this study would conclude the better drug which can be used in cases of shivering. Also the study will compare the side-effects of the treatment drug and the rate of recurrence after giving the treatment, ultimately reducing the patient discomfort.
AIM-
The purpose of this study is to compare Dexmedetomidine 0.5 μg/kg with that of Tramadol 0.5 mg/kg, both diluted in 10 ml NS given as IV infusion in 1 minute, in the treatment of shivering in patients undergoing elective surgery under spinal anaesthesia.
OBJECTIVE-
1.To assess the efficacy, potency and side-effects of Tramadol in treatment of shivering
2.To assess the efficacy, potency and side-effects of Dexmedetomidine in treatment of shivering
3.To compare the efficacy, potency and side-effects of both the drugs
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 21.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA Grade I and II
- •Patients admitted for lower abdominal and lower limb surgeries.
排除标准
- •Patients with cardiopulmonary disease, hepatic disorder, respiratory and neurological disorder.
- •Allergy to the study drugs
- •Those with an initial heart rate < 50 beats/minute
- •Systolic blood pressure < 100 mmHg
- •Patient on narcotics or any other sedatives which alter the thermoregulation
- •Patients with recent history of febrile illness and those with history of malignant hyperthermia.
- •Contraindication to regional anaesthesia.
结局指标
主要结局
control of shivering
时间窗: 5 minutes
次要结局
- Recurrence of shivering(3 months)