Scleral Response to Intraocular Pressure (IOP)
Completed
- Conditions
- Glaucoma, Open-Angle
- Registration Number
- NCT03267862
- Lead Sponsor
- Johns Hopkins University
- Brief Summary
The study evaluated changes in the depth of the lamina cribrosa at different eye pressures.
- Detailed Description
Participants were glaucoma patients who during routine care were observed at different eye pressures. Images taken with an optical device that is routinely used in such patients were analysed.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 27
Inclusion Criteria
- glaucoma patients
Exclusion Criteria
- non-glaucoma patients
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Anterior lamina cribrosa depth change Up to 2 months Position of anterior lamina observed by optical coherence tomography (OCT) imaging. Measured in micrometers (um).
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link lamina cribrosa depth changes to open-angle glaucoma progression?
How does scleral deformation under varying intraocular pressure compare to standard glaucoma diagnostic methods?
What biomarkers correlate with lamina cribrosa depth changes in open-angle glaucoma patients?
Are there adverse events associated with optical coherence tomography in glaucoma monitoring?
What combination therapies show promise for open-angle glaucoma alongside IOP monitoring techniques?