Clinical Factors Associated With Position Sense in Patients With Multiple Sclerosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Gazi University
- Enrollment
- 44
- Locations
- 1
- Primary Endpoint
- Light touch-pressure sensation
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Sensory impairment is an important problem for patients with Multiple Sclerosis (MS). Although there is no complete loss of sensation in patients, 80% of patients have a significant sensory impairment. The sensory system plays an important role in providing the feedback required to perform motor tasks. Cutaneous sensation, especially in the sole of the foot, is very important in maintaining balance and gait. There are studies showing decreased foot sole sensation in MS patients. Another sensation that is important during motor tasks is the proprioceptive sensation.
The aim of this study is to examine the relationship between the sensation of foot sole and joint position, clinical features, attention, fatigue, body awareness and physical activity level in patients with MS.
Detailed Description
Patients with MS between 0-5,5 score according to the Extended Disability Status Scale (EDSS) and healthy individuals of similar age and sex to patients will be included in the study. The sensation of foot sole, joint position sensation, attention, fatigue, body awareness, and physical activity level will be evaluated. The investigators will use t-tests to compare for quantitative variables and chi-square for the categorical variables between groups. In addition, the investigators will examine the correlations between the sensation of the foot sole, joint position sensation, attention, fatigue, body awareness, and physical activity level using Pearson bivariate correlations.
Investigators
Cagla Ozkul
Research Assistant
Gazi University
Eligibility Criteria
Inclusion Criteria
- •18-65 years of age
- •Having a diagnosis of "Multiple Sclerosis"
- •Relapse free in the last 3 mounts
- •Ambulatory status (Expanded Disability Status Scale score ≤ 6 )
- •No diagnosis of depression
Exclusion Criteria
- •Any cardiovascular, orthopedic, visual, and hearing problems that may affect the results of the research
Outcomes
Primary Outcomes
Light touch-pressure sensation
Time Frame: 10 minutes
Light touch-pressure sensation will be assessed using a full Semmes-Weinstein Monofilament (SWM) test kit (North Coast Medical, San Jose, CA, USA).
Knee proprioception
Time Frame: 10 minutes
Knee proprioception will be evaluated with the active joint reposition test using the isokinetic system (Cybex Norm, Humac, CA, USA).
position sensation of knee joint
Time Frame: 5 minutes
Open kinetic chain position of both knees will be evaluated using a Dualer IQ Digital Inclinometer (J-Tech Medical, Midvale, UT, USA).
Vibration sensation
Time Frame: 10 minutes]
Duration of vibration sensation will be measured using 128-Hz frequency tuning fork (Elcon1 Medical Instruments, Tuttlingen, Germany).
Secondary Outcomes
- Physical Activity(10 minutes)
- Body Awareness(5 minutes)
- Fatigue Severity(5 minutes)
- attention(5 minutes)