It is study on what happens to patients with liver disease who are hospitalized because their condition suddenly worsens.
Not Applicable
- Conditions
- Health Condition 1: K74- Fibrosis and cirrhosis of liver
- Registration Number
- CTRI/2024/02/062896
- Lead Sponsor
- Govind Ballabh Pant Institute of Post Graduate Medical Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Diagnosed cases of chronic liver disease presenting with acute Decompensation with or without prior Decompensation
Exclusion Criteria
1. Acquired or inherited immunodeficiency
2. Prior liver transplant
3. On any immunosuppressive therapy
4. Acute on chronic liver failure
5. Confirmed pregnancy
6. Patient with life-threatening chronic condition like uncontrolled diabetes mellitus, acute Decompensated heart failure, end stage renal disease, severe COPD.
7. Diagnosed case of Hepatocellular carcinoma
8. Extra-hepatic malignancy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The proportion of Pre-ACLF, UDC (unstable decompensated cirrhotic), SDC (stable decompensated cirrhotic) in cirrhotic patients who are admitted with an episode of Acute decompensation.Timepoint: Patients will be followed at following intervals - At admission, At 2 weeks, At 1 month, At 2nd month, At 3rd month
- Secondary Outcome Measures
Name Time Method The clinical & biochemical predictors of mortality & development of ACLF during the follow-up period. <br/ ><br>The clinical & biochemical predictors of development of stable decompensated cirrhotic during the follow-up period.Timepoint: Patients will be followed at following intervals - At admission, At 2 weeks, At 1 month, At 2nd month, At 3rd month