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临床试验/NL-OMON51729
NL-OMON51729尚未招募不适用

Effect of diEtaRy fructose on fructose kinetics in type 2 dIabetEs - ERIE

Academisch Medisch Centrum0 个研究点目标入组 40 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
40

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • - 40 T2D patients (20 Caucasian and 20 SAS)
  • - 40-70 years
  • - BMI 25-35
  • - Stable anti diabetic drugs for 3 months (metformin is obligatory)
  • - Stable medication uses past 3 months
  • - Able to give informed consent

排除标准

  • - Proton-pump inhibitor usage (known to effect gut microbiota)
  • - GLP1 or insulin use (known to effect gut microbiota)
  • - Antibiotic for the past 3 months (known to effect gut microbiota)
  • - Probiotic or symbiotic usage (known to effect gut microbiota)
  • - Pregnant women
  • - Chronic illness (including a known history of heart failure, renal failure
  • (eGFR <30 ml/min), pulmonary disease, gastrointestinal disorders, or
  • hematologic diseases), or other inflammatory diseases
  • - Active infection
  • - Previous intestinal (e.g., bowel resection/reconstruction) surgery
  • - Smoking (due to its influence on gut microbiome)
  • - Vegetarian diet (since they have different microbiota)
  • - >6 alcohol units per day or >14 alcohol units per week
  • - Active malignancy
  • - HbA1c >9% (75mmol/mol)
  • - The subject is already involved in a clinical trial

研究者

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