CORONARY PLAQUE CHARACTERIZATION USING 128-SLICE CT ANGIOGRAPHY IN SYMPTOMATIC PATIENTS FROM RURAL CENTRAL INDIA
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- To evaluate the prevalence and morphological characteristics of coronary plaques (calcified, non-calcified, and mixed) using 128-slice coronary CTangiography (CCTA) in symptomatic patients from rural Central India.
研究概览
简要总结
This 2-year prospective observational cross-sectional study will evaluate symptomatic patients with suspected coronary artery disease using 128-slice coronary CT angiography. Plaques will be classified as calcified, non-calcified, or mixed, and stenosis severity graded. Associations between plaque types and clinical risk factors such as hypertension, diabetes, dyslipidemia, smoking, and family history will be assessed. The study aims to enhance non-invasive CAD diagnosis, identify high-risk plaques, and provide regional data for targeted prevention and management strategies.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with chest pain, dyspnoea, palpitations, syncope, fatigue, reduced exercise tolerance, or a positive family history of CVD, referred for CCTA with suspected CAD, will be included Patients providing written informed consent Stable heart rate.
排除标准
- •Known hypersensitivity to iodinated contrast agents Renal impairment Uncontrolled arrhythmias or very high heart rates Pregnancy Poor image quality due to motion artifacts.
结局指标
主要结局
To evaluate the prevalence and morphological characteristics of coronary plaques (calcified, non-calcified, and mixed) using 128-slice coronary CTangiography (CCTA) in symptomatic patients from rural Central India.
时间窗: To evaluate the prevalence and morphological characteristics of coronary plaques (calcified, non-calcified, and mixed) using 128-slice coronary CT angiography (CCTA) in symptomatic patients from rural Central India.
To assess the degree of coronary artery stenosis associated with different types of coronary plaques.
时间窗: To evaluate the prevalence and morphological characteristics of coronary plaques (calcified, non-calcified, and mixed) using 128-slice coronary CT angiography (CCTA) in symptomatic patients from rural Central India.
To explore correlations between coronary plaque characteristics and clinical risk
时间窗: To evaluate the prevalence and morphological characteristics of coronary plaques (calcified, non-calcified, and mixed) using 128-slice coronary CT angiography (CCTA) in symptomatic patients from rural Central India.
factors such as hypertension, diabetes, dyslipidaemia, smoking, and family
时间窗: To evaluate the prevalence and morphological characteristics of coronary plaques (calcified, non-calcified, and mixed) using 128-slice coronary CT angiography (CCTA) in symptomatic patients from rural Central India.
history.
时间窗: To evaluate the prevalence and morphological characteristics of coronary plaques (calcified, non-calcified, and mixed) using 128-slice coronary CT angiography (CCTA) in symptomatic patients from rural Central India.
次要结局
未报告次要终点
研究者
MUSKAN YADAV
JAWAHARLAL NEHRU MEDICAL COLLEGE ACHARYA VINOBA BHAVE RURAL HOSPITAL SAWANGI MEGHE WARDHA