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The reliability of new point-of-care instruments for breath analysis in children with asthma and cystic fibrosis (CF), and healthy controls

Completed
Conditions
asthma
cystic fibrosis (CF)
10006436
Registration Number
NL-OMON44692
Lead Sponsor
Medisch Universitair Ziekenhuis Maastricht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
60
Inclusion Criteria

Study Population:
3 groups of children and adolescents aged 6-20 years will be randomly selected:
* 20 healthy children and adolescents
* 20 children and adolescents with asthma
* 20 children and adolescents with CF;
* Children and adolescents aged 6 to 20 years
* Healthy group: See exclusion criteria
* Asthma group: Doctor*s diagnosed asthma
* Cystic Fibrosis group: a diagnosis of cystic fibrosis, confirmed by a sweat test or genetic analysis

Exclusion Criteria

* Recent course of prednisone or antibiotics (< 1 month before test)
* Passive smoking
* Other chronic inflammatory disease (e.g. inflammatory bowel disease, rheumatic disease, auto-immune disease)
* Healthy children and adolescents:
* No current or history of respiratory symptoms (by using ISAAC questionnaire)
* No current or history of allergic rhinitis (by using ISAAC questionnaire)

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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