Implementation of a Pharmacy-Intervention to Enhance Prescription and Use of Lipid-Lowering Drugs

Not Applicable

Completed

• Conditions: Cardiovascular Diseases
• Interventions: Other: intensive implementation programme; Other: control

• Registration Number: NCT00509717
• Lead Sponsor: Radboud University Medical Center

Brief Summary

The purpose of this study is to determine the effectiveness of maximal support of community pharmacies to implement a pharmaceutical care model for improving underprescription and treatment persistence regarding lipid-lowering medication in patients with cardiovascular disease.

Detailed Description

Cardiovascular disease is the main cause of death in large parts of the world. Next to life style changes, pharmaceutical treatment is a keystone in the treatment of cardiovascular disease. Despite the strong evidence for the effectiveness of lipid-lowering therapy, less than half of the people eligible are treated. With specific medication searches in the community pharmacy database, an easy tool for detecting patients who are undertreated is available. Based on this tool, a pharmaceutical care model for improving underprescription and treatment persistence regarding lipid-lowering medication in patients with cardiovascular disease was constructed.

Moreover, it is not known yet how to implement this pharmaceutical care model in community pharmacies effectively. With multifaceted interventions the behaviour of health professionals can be changed. In this study the effectiveness of a maximal support strategy, including interactive educational meetings, reminders, audit and feedback, is compared to a minimal implementation strategy.

Study Timeline

• Study Start: 2006-10
• Study First Submitted: 2007-02-28
• Study First Submitted QC: 2007-07-30
• Study First Posted: 2007-07-31
• Primary Completion: 2008-02
• Study Completion: 2008-03
• Status Verified: 2008-07
• Last Update Submitted: 2008-07-09
• Last Update Posted: 2008-07-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• pharmacies: resident in the south of the Netherlands
• patients: with antiplatelet therapy and without lipid-lowering medication

Exclusion Criteria

for patients:

• terminal disease
• severe mental disorder

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
experimental	intensive implementation programme	-
control	control	-

Primary Outcome Measures

Name	Time	Method
The percentage of selected (=undertreated) patients receiving at least one prescription for lipid-lowering medication.	six months after the general practitioner received the list with selected patients

Secondary Outcome Measures

Name	Time	Method
Differences in prescribing for age categories and co-medication.	six months

Trial Locations

Locations (1)

UMC St Radboud, Scientific Institute for Quality of Healthcare; 🇳🇱 Nijmegen, NL, Netherlands