Associations Between Vision and Brain Function

• Conditions: Healthy; Vision; Disorder, Loss

• Registration Number: NCT04226729
• Lead Sponsor: Sun Yat-sen University

Brief Summary

Case-control studies and meta-analysis have reported that several ocular features, especially the thickness of the peripapillary retinal nerve fiber layer and visual acuity, are related to the brain degeneration and cognitive impairment. In our study, we aim to quantitatively assess ocular features using structural and functional indicators and define its associations with brain development and intelligence in children.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-12-30
• Study First Submitted QC: 2020-01-10
• Study First Posted: 2020-01-13
• Study Start: 2022-01-25
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-14
• Last Update Posted: 2022-08-16
• Primary Completion: 2022-12-30
• Study Completion: 2023-04-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• age from 3 to 12 years old

Exclusion Criteria

• diagnosed with nervous system disease before

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the visual information processing function	recorded at enrollment	collected with the electroencephalogram
best corrected visual acuity	recorded at enrollment	collected with visual acuity chart

Secondary Outcome Measures

Name	Time	Method
intraocular pressure	recorded at enrollment	the intraocular pressure of both eyes
refractive status	recorded at enrollment	the refractive status of both eyes
fundus picture	recorded at enrollment	the fundus pictures of both eyes

Trial Locations

Locations (1)

Zhongshan Ophthalmic Center, Sun Yat-sen Univerisity; 🇨🇳 Guangzhou, Guangdong, China