Impact of Previous Open Renal Surgery on Percutaneous Nephrolithotomy Complications

Completed

• Conditions: Open Renal Surgery; Percutaneous Nephrolithotomy; Complications

• Registration Number: NCT07097883
• Lead Sponsor: Sohag University

Brief Summary

This study compared percutaneous nephrolithotomy (PCNL) complications in cases with or without previous renal surgery.

Detailed Description

Percutaneous nephrolithotomy (PCNL) is a cornerstone in managing large renal calculi. However, in patients with a history of previous open renal surgery (POS), retroperitoneal scarring, altered anatomy, and vascular complications may influence PCNL outcomes.

The literature remains inconsistent regarding whether POS negatively impacts PCNL success or increases complications. Therefore, this study aims to clarify the comparative safety and efficacy of PCNL in patients with and without prior open renal surgery.

Study Timeline

• Study Start: 2017-01-01
• Primary Completion: 2020-08-01
• Study Completion: 2020-08-01
• Status Verified: 2025-07
• Study First Submitted: 2025-07-24
• Study First Submitted QC: 2025-07-24
• Last Update Submitted: 2025-07-24
• Study First Posted: 2025-07-31
• Last Update Posted: 2025-07-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Adult patients (≥18 years).
• Both sexes.
• Undergoing percutaneous nephrolithotomy (PCNL) for renal calculi >2 cm.

Exclusion Criteria

• Active urinary tract infection.
• Elevated serum creatinine >2.0 mg/dL.
• Pregnancy.
• Uncontrolled coagulopathy.
• Significant cardiopulmonary comorbidities.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hospital stay duration	Till the discharge from hospital (Up to two weeks)	Lenght of hospital stay was recorded from the admission till the discharge from hospital.

Secondary Outcome Measures

Name	Time	Method
Serum creatinine level	Preoperatively	Serum creatinine level was recorded.
Incidence of patients who need for auxiliary procedure	24 hours postoperatively	Incidence of patients who need for auxiliary procedure were recorded.

Trial Locations

Locations (1)

Sohag University; 🇪🇬 Sohag, Egypt