IRCT201207013043N6已完成2 期
Evaluation of protective effects of silymarin on cisplatin induced nephrotoxicity in patients with upper gastrointestinal adenocarcinoma
tehran university of medical science,0 个研究点目标入组 58 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 58
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 139 years(—)
- 性别
- All
入选标准
- •inclusion criteria (age>18 years; diagnosed and measurale upper gasterointestinal adenocarcinoma; no swallow problem; would like to participate in the study; GFR>45ml/min/1.73m2) Exclusion criteria( end stage renal disease, requiring dialysis, post transplantation; receiving contrast media during last 72 hours; chronic use of corticosteroids; chronic use of ACEI; untreated hypo-and hyperthyroidism; ejection fraction<60%; active urinary tract infection; iver disease (5fold increase of liver enzyme in asymptomatic or 3 fold increase in syptomatic; ; use of other nephrotoxic agents such as aminoglycoside, amphotricin; karnofsky performance status <70)
排除标准
- 未提供
研究者
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