The offline effects of transcranial direct current stimulation (tDCS) on postural balance control after stroke. - Effects tDCS after stroke

Radboud Universitair Medisch Centrum0 个研究点目标入组 37 人开始时间: 待定最近更新: 2024年6月11日

适应症

试验速览

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•Only people over 18 years old in the chronic phase after experiencing a supratentorial unilateral stroke (> 6 months in the past) that resulted in hemi pareses will be recruited for this study. Furthermore, healthy controls of similar age and with a similar male:female ratio will be enrolled in the study and 10 healthy young controls (18 - 30 year) are included for the tDCS sessions only.

•Serious head trauma or head, neck or shoulder surgery in the past
•Large or ferromagnetic metal parts in the upper body (except for dental fillings and wire)
•Implanted cardiac pacemaker or neurostimulator (too close to the head) or Venous Access Port
•Pregnancy
•Skin diseases at intended electrode sites (tDCS or EMG electrodes)
•Any prescribed medication that can alter cortical excitability (e.g. anti epileptics, tricyclic anti-depressives or benzodiazepines) within two weeks prior to participation.
•Participated in a TMS or tCS study less than 1 year ago.
•Suffering from claustrophobia
•Suffering from epilepsy
•Irremovable piercing or medical patch
•Any neurological or orthopaedic disorder (other than stroke) that may interfere with the MRI outcomes of interest and/or with the performance on the movement tasks
•Disorders of hearing, which cannot be corrected to normal.
•Medication negatively affecting balance or reaction times (e.g. neuroleptics, antidepressants, anticonvulsants, sedatives)
•Severe cognitive impairment (mini mental state examination (MMSE) <24)

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