Evaluation of the Predictive Nature of the Postoperative CRP on Postoperative Recovery in Patients Undergoing Colorectal Resection
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 174
- 试验地点
- 2
- 主要终点
- C-reactive protein rate
研究概览
简要总结
Colic and rectal resection represents a majority of hospitalizations in visceral surgery. The objective of this study was to evaluate the prognostic of inflammatory markers dosage (CRP, procalcitonin and venous lactate) on the postoperative recovery after colorectal surgery and on the length of stay.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Upper age to 18 years
- •Planned hospital stay for a colonic resection with anastomosis without permanent or temporary digestive bypass
- •Patient with pre-operative CRP lower or egal to 172 mg/L
- •No opposition at the participation of the study
- •Expected patient return home after surgery (or convalescent home or not medicalized institution)
排除标准
- •Patient under guardianship
- •Protected or private patient freedom
- •Minor patient
- •Colectomy surgery with digestive bypass or digestive anastomosis
- •Complex combined surgery (significantly intestinal resection associated, another surgical procedure that can interfere with postoperative CRP)
- •General inflammatory disease susceptive to modify dosage values
- •Anti-inflammatory therapy (AINS/ corticosteroids/ immunosuppressive)
- •Patient unable to understand the study
研究组 & 干预措施
C-reactive protein dosage
干预措施: C-reactive protein dosage (Other)
结局指标
主要结局
C-reactive protein rate
时间窗: 3 postoperative days
The time of postoperative recovery will be compared to the CRP values at 3 postoperative days. The postoperative recovery is a composite endpoint defined by : * no pain \> 2 on the VAS scale * presence of a gaseous bowel * patient autonomy in terms of ambulation and body care (IRM 5-6) * no fever
C-reactive Protein Rate
时间窗: 5 postoperative days
Comparison C-reactive protein levels \< 172 mg/l at 3 post operative day with composite endpoint postoperative recovery (fever, absence of pain \>2, intestinal gas transit and patient autonomy for mobility and body care) at 5 post operative day. The Specificity, Sensitivity, PPV, NPV of C-Reactive Protein Levels at Day 3 Post-operative in Determining Day 5 Post-operative Recovery
次要结局
未报告次要终点