Feasibility study of fluorescence-guided surgery using 5-aminolevulinic acid in head and neck cancer.
Not Applicable
- Conditions
- Head and neck cancer
- Registration Number
- JPRN-UMIN000019448
- Lead Sponsor
- Department of Otorhinolaryngology-Head and Neck Surgery, Kitasato University School of Medicine
- Brief Summary
Fluorescence imaging using ALA did not detect significant signal in head and neck cancer. Because tumor differentiation presumably affected the unfavorable results, the case with poor differentiated squamous cell carcinoma (SCC) came to prospective objective. However, there was no candidate meeting conditions. Thus, the fluorescence imaging using ALA might be unpractical at least in the case with differentiated SCC which fills majority of head and neck cancer.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 3
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with porphyria, pregnancy, severe cardiac, renal or hepatic disorders or poor general condition
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The comparison of fluorescence emission and histological lesion in resected specimens
- Secondary Outcome Measures
Name Time Method Complications Recurrence rate