Home based Intensive Nutrition Therapy versus Standard Medical Treatment in patients with Frailty and Sarcopenia in decompensated cirrhosis:An Open Label Randomised Trial - HINT TRIA

Postgraduate Institute of Medical Education and Research0 个研究点目标入组 100 人开始时间: 待定最近更新: 2023年2月6日

试验速览

暂无简介。

•A.Age >= 18 years
•B.Diagnosis of cirrhosis confirmed by clinical, biochemical, compatible radiology, histology
•C.Presence of frailty and sarcopenia

•A.Patients with CTP score more than 10
•Obese patient (BMI >25kg/m2)
•B.Patients with active malignancy, hepatocellular carcinoma and, the end-stage renal disease will be excluded from the study.
•C.Patients having prior study enrolment or enrolment in another conflicting study will be excluded.
•D.Patients, who are not willing to participate in the study will be excluded.
•E.Patients who are participating in other clinical trials within past 3 months.
•F.Patients who has an active evidence of infection
•G.Patients who had acute organic brain disease in the past 6 months
•H.Patients who has severe hemodynamic instability, serious heart disease, severe bradycardia or tachycardia at rest
•I.Patients having renal failure (creatinine clearance rate <=60 mL/min/1.73 m2).
•J.Patients who are not able to perform the strength exercise; severe cognitive impairment (Mini-Mental State Examination <=17), overt hepatic encephalopathy or patients who had physical disability.

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