The effect of vitamin E and zinc supplementation on serum levels of vitamin E, zinc, and antioxidants in beta thalassemia major patients
Phase 2
- Conditions
- Beta Thalassemia major.Cooley's anaemia, Severe beta thalassaemia
- Registration Number
- IRCT138811033139N1
- Lead Sponsor
- Drug Applied Research Center, Nutrition Research Center, Tabriz University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
history of continuous treatment with blood transfusion and desferal as a chellator agent.
Exclusion criteria: history of diabetes mellitus, smoking, hepatitis B and C and consumption of any supplements at least three month prior to the study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum level of vitamin E. Timepoint: 3 months. Method of measurement: Enzymatic analysis.;Serum level of zinc. Timepoint: 3 months. Method of measurement: enzymatic analysis.;Glutathion peroxidase activity. Timepoint: 3 months. Method of measurement: enzymatic analysis.;Body mass index. Timepoint: 3 months. Method of measurement: Dividing weight (kg) by the second power of height(m).
- Secondary Outcome Measures
Name Time Method Appetite. Timepoint: 3 months. Method of measurement: Questionnaire.;Wellbeing. Timepoint: 3 months. Method of measurement: questionnaire.