Evaluation of Stroke Volume Variation Derived From NICOM as a Predictor of Fluid Responsiveness in Neurosurgical Patients: A Gray Zone Approach
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Neurological Diseases or Conditions
- Sponsor
- Samsung Medical Center
- Locations
- 1
- Primary Endpoint
- Stroke volume variation
- Status
- Withdrawn
- Last Updated
- 9 years ago
Overview
Brief Summary
Optimal fluid management has been considered as crucial part to determine postoperative outcome and organ function. Recently developed, non invasive cardiac output measurement(NICOM, Cheetah Medical, Portland, OR)has enabled continuous cardiac output(CO) monitoring just by attaching electrode on chest wall. Moreover, CO and SSV derived from NICOM have been demonstrated as predictors of fluid responsiveness. Therefore, the aim of this study is to evaluate stroke volume variation derived from NICOM as a predictor of fluid responsiveness in neurosurgical patients. In addition, we plan to reveal inconclusive patients using gray zone approach.
Detailed Description
Optimal fluid management has been considered as crucial part to determine postoperative outcome and organ function. Many reports have focussed on evaluation of fluid responsiveness using various parameters such as pulse pressure variation (PPV) or stroke volume variation (SSV) derived from invasive or semi-invasive monitoring. Recently developed, non invasive cardiac output measurement(NICOM, Cheetah Medical, Portland, OR)has enabled continuous cardiac output(CO) monitoring just by attaching electrode on thorax. Moreover, CO and SSV derived from NICOM have been demonstrated as predictors of fluid responsiveness. Therefore, the aim of this study is to evaluate stroke volume variation derived from NICOM as a predictor of fluid responsiveness in neurosurgical patients. In addition, we plan to reveal inconclusive patients using gray zone approach.
Investigators
Jong Hwan Lee
Assistant Professor
Samsung Medical Center
Eligibility Criteria
Inclusion Criteria
- •ASA I or ASA II patients aged 20-80 undergoing neurosurgery in supine position
Exclusion Criteria
- •Pre-existing arrythmic disorders
- •Congestive heart failure required medical treatment
- •Preoperative Creatinine 1.3mg/dl
- •observing self respiration during the study interventions
- •Bleeding tendency
- •Severe brain edema
Outcomes
Primary Outcomes
Stroke volume variation
Time Frame: 5min following the end of rapid fluid infusion
5min following the end of rapid fluid infusion: 5 min after the end of fluid loading
Secondary Outcomes
- Correlation with pulse pressure variation(5 min following the end of rapid fluid infusion)