Electroencephalography-based investigation of the effects of oral desmopressin on improving slow-wave sleep time in nocturnal polyuria patients - The DISTINCT study

Torimoto Kazumasa0 sites20 target enrollmentDecember 9, 2019

Overview

No summary available.

Registry

who.int

Start Date

December 9, 2019

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Sex

Male

Sponsor

Torimoto Kazumasa

•1 Nocturnal urinary frequency \= and \>2 and Nocturnal polyuria index (nocturnal urinary volume/24 hours urinary volume) \= and \>0\.33
•2 Hours of undisturbed sleep before registration \= and \<2\.5 hours
•3 Concentration of serum sodium \= and \>135 mEq/L
•4 Creatinine clearance or eGFR (estimate glomerular filtration rate) \= and \>50 mL/min/1\.73m^2

•1 Hyponatremia or the history (Concentration of serum sodium \<135 mEq/L)
•2 Habitual or Psychogenic polydipsia
•3 Heart failure or the history or suspected heart failure
•4 Fluid retention that requires diuretic treatment or the history
•5 Antidiuretic hormone incompatible secretion syndrome
•6 Moderate or severe renal failure (Creatinine clearance or eGFR \<50 mL/min/1\.73m^2\)
•7 Hypersensitivity to desmopressin or the history
•8 During or scheduled administration of thiazides, thiazide\-like diuretics, loop diuretics
•9 During or scheduled administration of corticosteroids
•10 Carciac pacemaker implantation