Investigating the effect of standard treatment of three drugs empagliflozin + linagliptin + metformin (trijardi xr) on controlling blood sugar, weight, vitamin D and lipid profile of patients
Phase 2
- Conditions
- type 2 Diabetes.Type 2 diabetes mellitus
- Registration Number
- IRCT20240215061021N1
- Lead Sponsor
- Dezfoul University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 28
Inclusion Criteria
bmi range between 25 and 45
Patients with diabetes resistant to treatment with gliclazide or metformin
Age more than 18 years
Hba1c should be between 7 and 10.5
Fbs less than 250
Gfr more than 30
No change in treatment =12 weeks before the study
be treated with metformin + sitagliptin combination drug
Exclusion Criteria
GFR<30
History of recurrent urinary tract infections
History of frequent urination
Bmi less than 25
ACS, STROKe or TIA in the last three months
Bariatric surgery at least two years ago
Be susceptible to lactic acidosis or pancreatitis
Dm1
Pregnancy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fasting blood sugar. Timepoint: before the start of the study and three months after the start of treatment. Method of measurement: Measurement through variable measurement by laboratory diagnostic kit.;HbA1c. Timepoint: before the start of the study and three months after the start of treatment. Method of measurement: Measurement through variable measurement by laboratory diagnostic kit.
- Secondary Outcome Measures
Name Time Method ipid profile. Timepoint: before the start of the study and three months after the start of treatment. Method of measurement: Measurement through variable measurement by laboratory diagnostic kit.;Vitamin D. Timepoint: before the start of the study and three months after the start of treatment. Method of measurement: Measurement through variable measurement by laboratory diagnostic kit.;BMI. Timepoint: before the start of the study and three months after the start of treatment. Method of measurement: How to calculate BMI: Weight (kg) / height squared (m2) BMI.