Comparison of analgesic action of two doses of dexmedetomidine, when used in addition to bupivacaine, in femoral nerve block given to reduce post operative pain after total knee replacement surgery
Not Applicable
Completed
- Conditions
- Health Condition 1: null- American Society of Anesthesiologists Physical status classes 1, 2Health Condition 2: M171- Unilateral primary osteoarthritisof knee
- Registration Number
- CTRI/2013/11/004168
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
ASA 1, 2 patients undergoing unilateral primary total knee replacement arthroplasty
Exclusion Criteria
ASA 3,4, bilateral, revision TKR,focal neurological deficits, pre existing peripheral neuropathy,uncontrolled diabetes mellitus,coagulation disorders
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quality of post operative analgesia as assessed by, <br/ ><br>1)VAS (0-10 scale; 0-no pain; 10-worst possible pain) <br/ ><br>â?¢pain at rest at 0, 4, 8, 12, 24, 48 hours after surgery <br/ ><br>â?¢pain at motion (knee flexion) at 12, 24, 48 hours after surgery <br/ ><br>2)Post operative opioid consumption: Total dose of PCA morphine consumed, dose of rescue analgesia used. <br/ ><br>3)Duration of analgesia: Time to first use of patient controlled analgesia <br/ ><br>Timepoint: Quality of post operative analgesia as assessed by, <br/ ><br>1)VAS (0-10 scale; 0-no pain; 10-worst possible pain) <br/ ><br>â?¢pain at rest at 0, 4, 8, 12, 24, 48 hours after surgery <br/ ><br>â?¢pain at motion (knee flexion) at 12, 24, 48 hours after surgery <br/ ><br>2)Post operative opioid consumption: Total dose of PCA morphine consumed, dose of rescue analgesia used. <br/ ><br>3)Duration of analgesia: Time to first use of patient controlled analgesia <br/ ><br>
- Secondary Outcome Measures
Name Time Method Adverse effects of dexmedetomidine in peripheral nerve block such as nausea, vomiting, pruritus, sedation, hypotension, bradycardia, neuropathy in the perioperative period will be recordedTimepoint: Adverse effects of dexmedetomidine in peripheral nerve block such as nausea, vomiting, pruritus, sedation, hypotension, bradycardia, neuropathy in the perioperative period will be recorded