Symbiotic and blood uremic toxins in hemodialysis patients
Phase 2
- Conditions
- end stage renal disease.Hypotension of hemodialysis
- Registration Number
- IRCT20160528028120N1
- Lead Sponsor
- Isfahan university of medical sciences; research assistant part
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 46
Inclusion Criteria
performing hemodialysis treatment 3-times per week for at least 4 hours each time,
not being pregnant or lactating
no history of active cancers (except for skin cancer)
no history of severe chronic conditions such as pulmonary, cardiovascular, and hepatic diseases
lack of gastrointestinal disorders, HIV disease, and psychiatric problems
Exclusion Criteria
those who used symbiotic, probiotic, prebiotic or antibiotics during 4 weeks preceding the study
those who used immune suppressive medicines, and anticoagulant agents
with severe edema
addiction to alcohol or drugs abuse
did not respond to the questions honestly
and reported any side effects due to synbiotic consumption
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Indoxyl sulfate. Timepoint: 1 and 8 weeks of treatment. Method of measurement: Eliza kit.;Crp. Timepoint: 1 and 8 weeks of treatment. Method of measurement: Eliza kit.
- Secondary Outcome Measures
Name Time Method Phenol. Timepoint: 1 and 8 weeks of treatment. Method of measurement: hplc.