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Clinical Trials/NCT03601208
NCT03601208
Unknown
Not Applicable

Comparison of Standard Venous Sampling for Measurement of Tacrolimus and Creatinine Versus Fingerprick Mitra® Volumetric Absorptive Microsampling in Adult Renal Transplant Recipients

Nottingham University Hospitals NHS Trust0 sites100 target enrollmentAugust 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Transplant;Failure,Kidney
Sponsor
Nottingham University Hospitals NHS Trust
Enrollment
100
Primary Endpoint
Comparison of creatinine and tacrolimus values for Mitra VAM (test) versus venous sampling (standard).
Last Updated
7 years ago

Overview

Brief Summary

Patients with kidney transplant have blood tests very often. This is normally done in hospital and using a needle inserted into the vein. Two tests are important for kidney transplant patients - creatinine to monitor the health of the kidney; and tacrolimus to measure the level of the medicine which prevents rejection. The investigators would like to compare a fingerprick microsampling method to the standard venous blood. The fingerprick test is the same done by patients with diabetes and we use a microsampling tip which looks like a cotton bud to draw up a small amount of blood. Each tip draws up exactly 10 microlitres which is two drops. The investigators want to compare the results of creatinine and tacrolimus done through the two methods. In the future, this would allow patients to do their creatinine and tacrolimus test at home. The tips dry completely and can be posted to a laboratory. We hope this will make life easier for transplant patients and also help them engage more with the care of their condition.

Registry
clinicaltrials.gov
Start Date
August 2018
End Date
January 2019
Last Updated
7 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Kidney transplant recipients. Taking tacrolimus

Exclusion Criteria

  • Unable to consent

Outcomes

Primary Outcomes

Comparison of creatinine and tacrolimus values for Mitra VAM (test) versus venous sampling (standard).

Time Frame: 3 months

Compare blood results for creatinine and tacrolimus using two different methods - Mitra volumetric absorptive microsamplers (VAM) versus venous blood (standard).

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