Ultrasound Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Cholecystectomy

Not Applicable

Recruiting

• Conditions: Laparoscopic Cholecystectomy; Modified Thoracoabdominal Nerve Block; Quadratus Lumborum Block

• Registration Number: NCT06588777
• Lead Sponsor: Ain Shams University

Brief Summary

This study aims to compare the efficacy of using Ultrasound guided modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) versus quadratus lumborum block for postoperative analgesia in laparoscopic cholecystectomy under general anesthesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-09-01
• Study First Submitted: 2024-09-01
• Study First Submitted QC: 2024-09-06
• Study First Posted: 2024-09-19
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-18
• Last Update Posted: 2025-01-22
• Primary Completion: 2025-08
• Study Completion: 2025-08

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• Adult patients aging ≥ 21 years to ≤ 70 of both sexes.
• Patients undergoing Laparoscopic cholecystectomy surgeries.
• ASA physical status classes I - II.

Exclusion Criteria

• Patient's refusal of procedure or participation in the study.
• ASA classes III or above.
• Coagulopathy and bleeding disorders.
• Evidence of Local skin infections at site of injection.
• Body mass index >40kg/m2
• A history of relevant local anesthetic allergy.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Time to first Rescue Analgesia	24 hours postoperative	Is to measure the first time to resque analgesia postoperative (24 hours)

Secondary Outcome Measures

Name	Time	Method
The total requirements of rescue analgesia Meperidine (pethidine) over the first 24 hours postoperative	24 hours postoperative
Heart rate	at intervals of 0 (PACU), 1, 2, 4, 6, 12, 18 and 24 hours postoperatively
Blood pressure	at intervals of 0 (PACU), 1, 2, 4, 6, 12, 18 and 24 hours postoperatively
Spo2 measuring	at intervals of 0 (PACU), 1, 2, 4, 6, 12, 18 and 24 hours postoperatively

Trial Locations

Locations (1)

Ainshams university hospitals; 🇪🇬 Cairo, Egypt