Ultrasound Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Cholecystectomy

Ain Shams University1 site in 1 country52 target enrollmentSeptember 1, 2024

ConditionsLaparoscopic Cholecystectomy Modified Thoracoabdominal Nerve Block Quadratus Lumborum Block

Overview

Phase: N/A
Intervention: Not specified
Conditions: Laparoscopic Cholecystectomy
Sponsor: Ain Shams University
Enrollment: 52
Locations: 1
Primary Endpoint: Time to first Rescue Analgesia
Status: Recruiting
Last Updated: 7 months ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study aims to compare the efficacy of using Ultrasound guided modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) versus quadratus lumborum block for postoperative analgesia in laparoscopic cholecystectomy under general anesthesia.

Registry

clinicaltrials.gov

Start Date

September 1, 2024

End Date

December 30, 2025

Last Updated

7 months ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Ain Shams University

Responsible Party

Principal Investigator

Ahmed Hassan Helmy

Clinical Doctor

Ain Shams University

Eligibility Criteria

Inclusion Criteria

•Adult patients aging ≥ 21 years to ≤ 70 of both sexes.
•Patients undergoing Laparoscopic cholecystectomy surgeries.
•ASA physical status classes I - II.

Exclusion Criteria

•Patient's refusal of procedure or participation in the study.
•ASA classes III or above.
•Coagulopathy and bleeding disorders.
•Evidence of Local skin infections at site of injection.
•Body mass index \>40kg/m2
•A history of relevant local anesthetic allergy.

Outcomes

Primary Outcomes

Time to first Rescue Analgesia

Time Frame: 24 hours postoperative

Is to measure the first time to resque analgesia postoperative (24 hours)

Secondary Outcomes

Spo2 measuring(at intervals of 0 (PACU), 1, 2, 4, 6, 12, 18 and 24 hours postoperatively)
The total requirements of rescue analgesia Meperidine (pethidine) over the first 24 hours postoperative(24 hours postoperative)
Heart rate(at intervals of 0 (PACU), 1, 2, 4, 6, 12, 18 and 24 hours postoperatively)
Blood pressure(at intervals of 0 (PACU), 1, 2, 4, 6, 12, 18 and 24 hours postoperatively)