Aerobic Training, Aerobic-resistance Training and Glucose Profile (CGMS) in Type 2 Diabetes

Not Applicable

Completed

• Conditions: Diabetes Mellitus, Type 2; Treatment; Exercise
• Interventions: Behavioral: Acute aerobic-resistance exercise; Behavioral: Acute aerobic exercise

• Registration Number: NCT00887094
• Lead Sponsor: Hospital de Clinicas de Porto Alegre

Brief Summary

Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.

Detailed Description

Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.

Study Timeline

• Study First Submitted: 2009-04-22
• Study First Submitted QC: 2009-04-22
• Study First Posted: 2009-04-23
• Study Start: 2009-06
• Primary Completion: 2011-03
• Study Completion: 2011-04
• Status Verified: 2011-08
• Last Update Submitted: 2011-08-03
• Last Update Posted: 2011-08-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• Type 2 diabetic patients treated with diet and metformin, 35-65 years old

Exclusion Criteria

• Type 1 diabetic patients
• Treatment with insulin or sulphonylureas or glitazones
• Proliferative retinopathy
• Severe autonomic neuropathy
• Coronary artery disease
• Baseline fasting plasma glucose>200 mg/dl
• Peripheral artery disease
• Amputation
• Heart failure
• Diabetic nephropathy
• Renal failure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Aerobic-resistance exercise	Acute aerobic-resistance exercise	One bout of aerobic-resistance physical training will be performed on a cycle ergometer added by a strenght training for 50 min (total)
Aerobic exercise	Acute aerobic exercise	One bout of aerobic physical training will be performed on a cycle ergometer for 50 min

Primary Outcome Measures

Name	Time	Method
Reduction of the prevalence of hyperglycemic peaks during a 24-h period after a bout of aerobic or aerobic/resistance exercise in type 2 diabetes patients on metformin/diet therapy.	24h

Trial Locations

Locations (1)

Hospital de Clinicas de Porto Alegre; 🇧🇷 Porto Alegre, RS, Brazil