Phase2 study of platinum doublet with pemetrexed in non-squamous non-small cell lung cancer with brain metastases.
Phase 2
- Conditions
- on-small cell Lung Cancer
- Registration Number
- JPRN-UMIN000007643
- Lead Sponsor
- orth Japan Lung Cancer Study Group
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
Not provided
Exclusion Criteria
1) Symptomatic brain metastases 2) Radiotherapy for brain metastases 3) Interstitial lung disease or lung fibrosis detectable or chest X-ray 4) Taking systematic administration of steroid for more than 4 weeks 5) Pleural or cardiac effusion that needs to drain 6) Severe comorbidities 7) Active co-existent malignancies 8) Pregnant patients 9) Other conditions inadequate for this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Disease control rate in brain lesions
- Secondary Outcome Measures
Name Time Method Response Rate Progression-free Survival Overall Survival Safety