Comparison of Outcome of Injection Sclerotherapy Versus Rubber Band Ligation for Second Degree Hemorrhoids

Not Applicable

Active, not recruiting

• Conditions: Hemorrhoid
• Interventions: Drug: Injection Sclerotherapy; Device: Rubber Band Ligation

• Registration Number: NCT07199673
• Lead Sponsor: Gulab Devi Hospital

Brief Summary

Objective of this study is to compare the outcome of Injection Sclerotherapy versus Rubber Band Ligation for second degree hemorrhoids in terms of bleeding and efficacy.

Detailed Description

There is a difference in the outcome of Injection Sclerotherapy versus Rubber Band Ligation for second degree hemorrhoids in terms of bleeding and efficacy.

Study Timeline

• Study Start: 2025-07-07
• Status Verified: 2025-09
• Study First Submitted: 2025-09-19
• Study First Submitted QC: 2025-09-26
• Last Update Submitted: 2025-09-26
• Study First Posted: 2025-09-30
• Last Update Posted: 2025-09-30
• Primary Completion: 2026-01-06
• Study Completion: 2026-01-06

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 128

Inclusion Criteria

• Adults aged between 18 and 75 who have been diagnosed with second-degree hemorrhoids

Exclusion Criteria

• Patients with thrombosed hemorrhoids, and those with serious comorbid conditions such as heart, kidney, or liver diseases, coagulation disorders, or severe anemia.

  • Individuals who have received treatment for hemorrhoids in the past six months.
  • Pregnant women.
  • Patients unable to commit to necessary follow-up appointments.
  • Patients with a history or current presence of colorectal cancer or anal malignancy.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group IST	Injection Sclerotherapy	5% phenol in almond oil
Group RBL	Rubber Band Ligation	rubber band is applied at the base of each hemorrhoid using Barron's Gun and Elise's tissue forceps.

Primary Outcome Measures

Name	Time	Method
Early per rectal Bleeding	24 hours	within 24 hours post-procedure

Secondary Outcome Measures

Name	Time	Method
Delayed Bleeding Per rectal	24 hours to 14th post operative day	24 hours to 14th post-operative day

Trial Locations

Locations (1)

Gulab devi Hospital Lahore; 🇵🇰 Lahore, Punjab Province, Pakistan