EUCTR2011-005235-22-IE进行中（未招募）不适用
Erythropoietin in Traumatic Brain Injury (EPO-TBI) - EPO-TBI
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 606
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Patients with non-penetrating moderate (GCS 9-12) or severe (GCS 3-8)
- •TBI admitted to the ICU who:
- •Are = 15 to = 65 years of age
- •Are < 24 hours since primary traumatic injury
- •Are expected to stay = 48 hours
- •Have a haemoglobin not exceeding the upper limit of the applicable
- •normal (ULN) reference range in clinical use at the treating institution
- •Have written informed consent from legal surrogate
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 600
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •GCS = 3 and fixed dilated pupils
- •History of DVT, PE or other thromboembolic event
- •Chronic hypercoagulable disorder, including known malignancy
- •EPO in the last 30 day
- •Pregnancy or lactation or 3 months post partum
- •Uncontrolled hypertension
- •Acute myocardial infarct within the past 12 months
- •Past history of epilepsy with seizures in past 3 months
- •Expected to die imminently
- •Inability to perform lower limb ultrasounds
- •lKnown sensitivity to mammalian cell derived products
- •Hypersensitivity
- •Pure red cell aplasia
- •End stage renal failure
- •Severe pre-existing physical or mental disability or severe co-morbidity
- •Treatment with any investigational drug within 30 days before
- •Not in the best interest of the patient
研究者
相似试验
进行中（未招募）
不适用
A study to see if erythropoietin can help patients recover better from headinjury.Traumatic brain injuryMedDRA version: 14.1Level: PTClassification code 10019196Term: Head injurySystem Organ Class: 10022117 - Injury, poisoning and procedural complicationsEUCTR2011-005235-22-DEMONASH UNIVERSITY606
进行中（未招募）
不适用
Erythropoietin for the repair of cerebral injury in very preterm infants, a randomized, double-blind, placebo-controlled, prospective, and multicenter clinical studyEUCTR2014-000612-34-ATniversitätsSpital Zürich120
撤回
2 期
Erythropoietin Effects After Traumatic Brain InjuryTraumatic Brain InjuryNCT00260052Medical College of Wisconsin
招募中
不适用
Erythropoitin to neuropritection in babies who didnt cry immediately after birth.CTRI/2021/08/035512DrSushma
已完成
不适用
Long Term Effects of Erythropoietin in Patients With Moderate to Severe Traumatic Brain InjuryTraumatic Brain InjuryNCT03061565Australian and New Zealand Intensive Care Research Centre356