Impact of Periodontitis Grading on Clinical and Bone Peri-Implant Health: Longitudinal, Prospective, 60-Month Follow-Up Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 主要终点
- Marginal bone level changes around dental implants evaluated radiographically.
研究概览
简要总结
This prospective cohort study evaluated the effect of periodontitis grading on peri-implant clinical and radiographic outcomes over a 60-month follow-up. Fifty-five partially edentulous patients were classified into three groups according to periodontal status: generalized aggressive periodontitis (Grade C), generalized chronic periodontitis (Grade B), and no history of periodontitis. A total of 92 implants (tissue- or bone-level) were placed and restored with single crowns, followed by biannual supportive periodontal therapy.
Peri-implant clinical parameters (probing depth, clinical attachment level, plaque index, and bleeding on probing), marginal bone level changes, peri-implantitis incidence, and implant survival were assessed up to 60 months after prosthetic loading.
The objective was to determine whether periodontal history and grading influence long-term peri-implant outcomes under maintenance therapy.
详细描述
This prospective cohort study was conducted to evaluate the long-term influence of a history of periodontitis on peri-implant clinical and radiographic outcomes in partially edentulous patients. Patients were classified according to their periodontal status into three groups: generalized aggressive periodontitis (currently classified as Grade C periodontitis), generalized chronic periodontitis (Grade B periodontitis), and individuals without a history of periodontitis.
A total of 55 patients received 92 dental implants, either tissue-level or bone-level, placed in healed sites and restored with single screw-retained crowns. All patients were enrolled in a structured supportive periodontal therapy program and were followed for 60 months after prosthetic loading.
Peri-implant and periodontal health were assessed longitudinally using clinical parameters (probing depth, clinical attachment levels, plaque accumulation, and bleeding on probing) as well as radiographic evaluation of marginal bone level changes. Assessments were performed at multiple time points throughout follow-up to monitor tissue stability and disease occurrence.
The primary aim of the study was to compare peri-implant outcomes among patients with different periodontal backgrounds and to determine whether a history and severity of periodontitis influence long-term implant success and disease incidence under strict maintenance conditions. Secondary outcomes included evaluation of marginal bone remodeling, incidence of peri-implantitis, and implant survival over time.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥ 18 years.
- •Previous diagnosis of aggressive periodontitis, chronic periodontitis, or no history of periodontitis.
- •Completion of periodontal treatment at least 1 year before study enrollment.
- •Enrollment in supportive periodontal therapy.
- •Plaque Index < 20% at study onset.
- •Bleeding on Probing < 20% at study onset.
- •Presence of at least one single edentulous space with adjacent teeth.
- •Sufficient bone and soft tissue volume for implant placement without the need for reconstructive procedures.
排除标准
- •Systemic conditions that contraindicate implant surgery.
- •Use of systemic antimicrobial therapy within 6 months before implant placement.
- •Untreated or uncontrolled aggressive periodontitis.
- •Untreated or uncontrolled chronic periodontitis.
- •Pregnancy or breastfeeding.
- •Need for bone grafting or soft tissue grafting procedures.
- •Current smokers or former smokers.
结局指标
主要结局
Marginal bone level changes around dental implants evaluated radiographically.
时间窗: Over a 60-month follow-up period.
Primary Outcome
次要结局
- Implant survival rate(60 months follow-up)
- Peri-implant probing depth (PPD) at follow-up visits(Over a 60-month follow-up period)
- Bleeding on probing (BoP) around implants(60 months follow-up)
研究者
Renato Casarin
Associate Professor of Periodontology
University of Campinas, Brazil