Reducing Perioperative S. Aureus Transmission Via Use of an Evidence-Based, Multimodal Program Driven by an Innovative Software Platform (OR PathTrac)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- S. Aureus Transmission
- Sponsor
- Georgetown University
- Enrollment
- 804
- Locations
- 1
- Primary Endpoint
- within-case S. aureus transmission
- Status
- Completed
- Last Updated
- 7 months ago
Overview
Brief Summary
Healthcare-associated infections (HAIs) occur frequently and are associated with patient harm. It is important that healthcare facilities take the necessary steps to prevent the spread of resistant bacteria. ESKAPE bacteria (Enterococcus, S. aureus, Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter spp.) are particularly pathogenic. Isolation of these pathogens from intraoperative reservoirs has been associated with postoperative infection development (i.e. surgical site infections). This project involves implementation of a software platform and bacterial collection system (OR PathTrac) that leverages the epidemiology of intraoperative bacterial transmission to guide dynamic, prospective improvements in perioperative infection control measures. The investigators will assess the effectiveness of OR PathTrac feedback in optimizing an evidence-based, multifaceted, perioperative infection control program.
Detailed Description
Our objective was to analyze the impact of surveillance feedback optimization of a multifaceted, perioperative infection control program on S. aureus transmission and SSIs. A multifaceted infection control program was implemented over 8 months (November 2018 to June 2019). A prospective cohort impact study was then conducted over 8 months (July 2019 to March 2020) to compare the incidence of within-case S. aureus transmission (primary outcome) and surgical site infection (secondary outcome) before (4.5 months) and after (3.5 months) implementation of surveillance feedback.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adult patients requiring anesthesia and intravenous catheter placement.
Exclusion Criteria
- •Pediatric patients, without requirement of anesthesia and/or intravenous catheter placement.
Outcomes
Primary Outcomes
within-case S. aureus transmission
Time Frame: From patient entry into the operating room until case end, up to 6 hours
S. aureus transmission events detected within a surgical case
Secondary Outcomes
- surgical site infection(Up to 90 days following surgery)