Accuracy Of Contrast Enhanced Mamography in Predicting Response of Breast Cancer Post Neoadjuvant Chemotherapy

• Conditions: Breast Cancer

• Registration Number: NCT05141279
• Lead Sponsor: Assiut University

Brief Summary

The aim of this work to evaluate the accuracy of contrast enhanced spectral mamography in predicting the response to NAC and assessment of residual disease in breast cancer patients

Detailed Description

This a prospective series ,will be performed for 50 patients diagnosed by biopsy as breast cancer who will be scheduled for surgery after completing the full coarse of neoadjuvant chemotherapy

Study Timeline

• Status Verified: 2021-11
• Study First Submitted: 2021-11-19
• Study First Submitted QC: 2021-11-19
• Last Update Submitted: 2021-11-19
• Study Start: 2021-12-01
• Study First Posted: 2021-12-02
• Last Update Posted: 2021-12-02
• Primary Completion: 2023-12-01
• Study Completion: 2024-01-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• patient confirmed diagnosed by early breast cancer decided to received neoadjuvant treatment
• locally advanced breast cancer
• operable metastatic breast cancer

Exclusion Criteria

• patient not candidate for NAC
• contrast allergy
• renal impairment
• pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Accuracy of contrast enhanced spectral mamography in the predicting of pathological response to NAC and assessment residual disease in breast cancer patients	Basline

Secondary Outcome Measures

Name	Time	Method
Assess best imaging modalities in pedict post neoadjuvant response	Baseline