A Study of the Human Anti-TNF Antibody Adalimumab for the Induction of Clinical Remission in Subjects With Crohn's Disease
- Conditions
- Crohn's Disease
- Registration Number
- NCT00055523
- Lead Sponsor
- Abbott
- Brief Summary
Purpose of the study is to test whether adalimumab can induce clinical remission in subjects with active Crohn's disease when compared to placebo (an inactive substance)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 300
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method (achievement of a CDAI <150) of adalimumab 40 mg and 80 mg vs. placebo at Week 4. comparison of the induction of clinical remission
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (43)
Clinical Pharmacology Study Group
🇺🇸Worcester, Massachusetts, United States
Mayo Clinic and Mayo Foundation
🇺🇸Rochester, Minnesota, United States
Northwest Gastroenterology
🇺🇸Bellevue, Washington, United States
Tacoma Digestive Disease Center
🇺🇸Tacoma, Washington, United States
Shafran Gastroenterology Center
🇺🇸Winter Park, Florida, United States
Wake Research Associates
🇺🇸Raleigh, North Carolina, United States
Digestive Disorders Associates
🇺🇸Annapolis, Maryland, United States
Rochester Institute for Digestive Diseases
🇺🇸Rochester, New York, United States
University of Chicago
🇺🇸Chicago, Illinois, United States
Long Beach Gastroenterology Assoc.
🇺🇸Long Beach, California, United States
Gastroenterology and Hepatology
🇺🇸Kansas City, Missouri, United States
Glenn Gordon, MD
🇺🇸Mexico, Missouri, United States
Digestive Health Specialists
🇺🇸Winston-Salem, North Carolina, United States
Northwest Gastroenterologists, S.C.
🇺🇸Arlington Heights, Illinois, United States
Charlotte Gastroenterology and Hepatology
🇺🇸Charlotte, North Carolina, United States
Altoona Center for Clinical Research
🇺🇸Duncansville, Pennsylvania, United States
Wisconsin Center for Advanced Research
🇺🇸Milwaukee, Wisconsin, United States
Inland Empire Gastroenterology
🇺🇸Spokane, Washington, United States
Research Solutions
🇺🇸Tulsa, Oklahoma, United States
Atlanta Gastroenterology Assoc.
🇺🇸Atlanta, Georgia, United States
Brigham and Women's Hospital
🇺🇸Boston, Massachusetts, United States
Peter Molloy, MD
🇺🇸Pittsburgh, Pennsylvania, United States
Gastroenterology Associates of the East Bay
🇺🇸Berkeley, California, United States
Cleveland Clinic Florida
🇺🇸Weston, Florida, United States
Southeastern Digestive & Liver Disease
🇺🇸Savannah, Georgia, United States
Massachusetts General Hospital
🇺🇸Boston, Massachusetts, United States
NY Center for Clinical Research
🇺🇸Lake Success, New York, United States
Long Island Clinical Research Associates
🇺🇸Great Neck, New York, United States
Daniel Present
🇺🇸New York, New York, United States
UNC School of Medicine
🇺🇸Chapel Hill, North Carolina, United States
Carolina Research Associates
🇺🇸Charlotte, North Carolina, United States
Charlottesville Medical Research
🇺🇸Charlottesville, Virginia, United States
Sharp Rees-Stealy Medical Group
🇺🇸San Diego, California, United States
Consultants for Clinical Research
🇺🇸Cincinnati, Ohio, United States
Oklahoma Foundation for Digestive Disease
🇺🇸Oklahoma City, Oklahoma, United States
Nashville Medical Research Institute
🇺🇸Nashville, Tennessee, United States
LSU School of Medicine
🇺🇸New Orleans, Louisiana, United States
New York Presbyterian Hospital
🇺🇸New York, New York, United States
Deaconess Billings Clinic Research Division
🇺🇸Billings, Montana, United States
Gastroenterology Assoc. of Fairfield Co.
🇺🇸Bridgeport, Connecticut, United States
Drug Research Services, Inc.
🇺🇸Metairie, Louisiana, United States
Gastroenterology Specialties, P.C.
🇺🇸Lincoln, Nebraska, United States
Diseases of the Digestive System
🇺🇸Chattanooga, Tennessee, United States