ISRCTN06022197
Completed
N/A
A pilot study of a randomised controlled trial of antipsychotic medication in comparison to cognitive behaviour therapy and a combined treatment in adults with psychosis
Greater Manchester West Mental Health NHS Foundation Trust (UK)0 sites75 target enrollmentMarch 20, 2014
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Topic: Mental Health Research Network
- Sponsor
- Greater Manchester West Mental Health NHS Foundation Trust (UK)
- Enrollment
- 75
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/29605187
Investigators
Eligibility Criteria
Inclusion Criteria
- •Current inclusion criteria as of 25/07/2014:
- •1\. In contact with mental health care services (under the care of a consultant)
- •2\. Either meet ICD\-10 criteria for schizophrenia, schizoaffective disorder or delusional disorder or meet entry criteria for an Early Intervention for Psychosis service (operationally defined using PANSS) in order to allow for diagnostic uncertainty in early phases of psychosis
- •3\. Aged 16\+
- •4\. Competent and willing to provide written, informed consent
- •5\. Score at least 4 on PANSS delusions or hallucinations or at least 5 on Suspiciousness/Grandiosity
- •6\. Help seeking
- •Previous inclusion criteria:
- •1\. Aged 18\+
- •2\. In contact with mental health services
Exclusion Criteria
- •Current exclusion criteria as of 25/07/2014:
- •1\. Primary diagnosis of alcohol/substance misuse
- •2\. Moderate or severe learning disability
- •3\. Score 5\+ on PANSS conceptual disorganisation
- •4\. Non\-English speaking
- •5\. Current receipt of structured CBT from a qualified psychologist in accordance with NICE guideline recommendations (as opposed to more generic psychosocial interventions) OR receipt of antipsychotics, OR receipt of either within the past 3 months.
- •6\. Immediate risk to self or others
- •7\. Organic Impairment
- •Previous exclusion criteria:
- •1\. Primary diagnosis of alcohol/substance dependence
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
N/A
Efficacy of patient-controlled paravertebral block for single intercostal video assisted thoracic surgeryPain in the postoperative periodSigns and SymptomsISRCTN24097424Second Affiliated Hospital of Zhejiang University260
Completed
N/A
The effect of fibre and fluids on gut health in adultsGastrointestinal healthDigestive SystemISRCTN42793297King's College London (UK)120
Completed
N/A
The treatment of severe atopic eczema trial (TREAT)Topic: Children, DermatologySubtopic: Children (all Diagnoses), Dermatology (Skin)Disease: All Diseases, DermatologySkin and Connective Tissue DiseasesSevere atopic eczemaISRCTN15837754King's College London (UK)103
Completed
N/A
A pilot trial of the mental health first aid eLearning course with UK medical studentsMental illnessMental and Behavioural DisordersISRCTN11219848The University of Nottingham50
Completed
N/A
Oxygen during activities in patients with lung scarringFibrotic lung diseasesRespiratoryISRCTN16427067Royal Brompton and Harefield NHS Foundation Trust (RB&HFT)80