Role of Regular Surveillance on Maintenance of Patency of an Arteriovenous Access
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 主要终点
- Number, type and technical success rate for elective interventions
研究概览
简要总结
Chronic Kidney disease (CKD) is a worldwide public health problem that classified into five stages (1). End stage renal disease (CDK stage 5) patients require a well-functioning vascular access (VA) for successful hemodialysis treatment (2). Types of VA include arteriovenous fistulae (AVFs) and arteriovenous grafts (AVGs). A vascular access is liable to early or late complications, and ultimately access failure. A meta-analysis showed that a 17% mean early access failure However recent studies have shown higher failure rates of up to 46%, with one year patencies between 52% to 83% (3). Low VA flow, thrombosis and loss of patency may result in under-dialysis that leads to increased morbidity, mortality and healthcare expenditure (4). In the majority of VAs, stenoses develop over variable intervals causing VA thrombosis and failure (5). If early detected and corrected, VA function and patency can be preserved and under-dialysis can be minimized or avoided. The aim of this study is to find out the role of periodic surveillance of VA in the detection of VA dysfunction and correctable lesions that may necessitate pre-emptive interventions to maintain VA patency and prevent VA loss
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ESRD Patients have functioning or failing VAs (AVFs or AVGs).
排除标准
- •ESRD patients have infected or failed VAs .
- •patientrefusal .
研究组 & 干预措施
ESRD Patients have functioning or failing VAs (AVFs or AVGs).
干预措施: duplex ultrasound (Device)
结局指标
主要结局
Number, type and technical success rate for elective interventions
时间窗: within one year of creation of the VA
次要结局
- secondary patency rate of the Arteriovenous Access after elective intervention(within one year of creation of the VA)
- number , type of complication that resulted from elective interventions(within one year of creation of the VA)
- primary patency rate of newly created Arteriovenous Access in assiut governorate(within one year of creation of the VA)
研究者
Ahmed Mohammed Rashed
resident of vascular surgery
Assiut University
