Efficacy of Electrical Pudendal Nerve Stimulation and Sacral in Treating Non-obstructive Neurogenic Urinary Retention
Not Applicable
Completed
- Conditions
- Urinary Retention
- Registration Number
- NCT06158074
- Lead Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
- Brief Summary
To observe the clinical effects and make a comparative study between efficacy of electrical pudendal nerve stimulation (EPNS) and sacral neuromodulation (SNM) , evaluate the advantages of EPNS in the treatment of neurogenic non-obstructive urinary retention, and provide a new method for the treatment of the disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 102
Inclusion Criteria
- Non-mechanical obstructive urinary retention occurs following relevant neurological system disorders (spinal cord injury, spina bifida，myelitis, cervical/thoracic disk disease, lesion following spinal anesthesia/spine surgery,lumbar/sacral spine intervertebral disc diseases, spinal stenosis, iatrogenic pelvic nerve lesions, sacral agenesis, peripheral neuropathy due to diabetes mellitus).
- With normal upper urinary tract function.
- Other therapies and medications potentially affecting the assessment of this therapy have been discontinued for at least two weeks before the interventional procedure.
- Patient with good compliance who is capable of cooperating with the follow-up requirements
Exclusion Criteria
- Patients with any suprapontine and pontine lesions
- Pregnant or lactating women
- Individuals whose symptoms show significant improvement after pharmaceutical and adjunctive therapy
- Individuals with concurrent acute or chronic prostatitis, prostate cancer, or conditions such as bladder neck stenosis, urethral stricture, or urethral injury
- High pathological risk factors (e.g., lymph node metastasis, resection margin involvement, bulky tumors)
- Individuals with concomitant obstructive urinary retention
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Bladder residual urine volume measured by ultrasound T0 (baseline); T1 (week 2); T2 (week 4) Bladder residual urine volume measured by ultrasound
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Shanghai research institute of acupuncture and meridian
🇨🇳Shanghai, China
Shanghai research institute of acupuncture and meridian🇨🇳Shanghai, China