Superior laryngeal nerve block for laryngeal sensory neuropathy
- Conditions
- Vocal cord dysfunctionaryngeal sensory neuropathyChronic CoughLaryngeal sensory neuropathyRespiratory - Other respiratory disorders / diseases
- Registration Number
- ACTRN12619000237189
- Lead Sponsor
- Department of Otolaryngology, Head and Neck surgery, Monash Health
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- All
- Target Recruitment
- 352
No objective evidence on formal testing and/or failure of adequate treatment to more common causes of treatment:
Respiratory Disease:
- Negative Testing: CXR or CT Chest, Broncho-provocation or Broncho-dilation testing
- No response to an 8 week empirical trial of inhaled corticosteroid
Allergic Disease:
- Negative Testing: Negative RAST or Skin prick testing for inhaled allergens
- No response to an 8 week empirical trial of intranasal and/or oral medications (e.g. Steroid, and/or Anti-histamine)
Laryngopharyngeal and Gastro-oesophageal Reflux Disease:
- Negative Testing: Negative Oral Salivary pepsin assay, or 24 hour dual probe pH/impedance monitoring.
- No response to an 8 week empirical trial of both acid reduction and alginate treatment.
Are on neuromodulator medications (ie. Tricyclic anti-depressants, SSRIs, Gabapentinoids)
Are on anti-tussive medications (ie Guafenasin)
Cannot tolerate an ‘in-office’ procedure
Known allergy or intolerance to bupivacaine and/or triamcinolone acetate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in symptom scores on vocal cord dysfunction questionnaire[3 months];Change in symptom scores on cough severity index[3 months]
- Secondary Outcome Measures
Name Time Method change in symptom scores on vocal cord dysfunction questionnaire[12 months];change in symptom scores on cough severity index[12 months]